What is in MycelPro-1?
Unflavored MycelPro-1 contains only one whole food ingredient - 100% mycelium. That’s it! No flavorings, sweeteners, or additives.
How does it taste?
Unflavored MycelPro-1 has a very neutral taste, which makes it perfect for adding to shakes/smoothies, a protein boost for plant milks, oatmeal, pancakes,baked goods, even coffee! One scoop in coffee provides 10g of protein, 34mg of Longevity Spermidine and doesn’t taste like mud!
Is MycelPro-1 a Mushroom?
No, our strain of Mycelium does not produce mushrooms or fruiting bodies. Most Fungal species do not produce mushrooms.
What is Mycelium?
Mycelium is the branching body of a fungus, composed of a network of thread-like filaments called hyphae. Mycelium is a sustainable material used in packaging, building, fashion, and food products like MycelPro-1.
Is it Certified Vegan? Non-GMO? Gluten Free? Allergens?
Yes! MCP-1 is Certified Vegan, Non-GMO, and Gluten Free and is suitable for KETO/Low-Carb/Atkins, Paleo, Mediterranean, Vegan, Vegetarian, and Whole-Food Plant Based Diets. MCP-1 contains NO US recognized allergens.
Is it Certified Organic?
We call MycelPro-1 “Better Than Organic!” because it is produced without any pesticides, herbicides, fungicides and glyphosate. Whereas some pesticides, herbicides and fungicides are permitted in organic farming. Also, Organic regulations do not set specific limits or require routine testing for heavy metals.
Was the mycelium tested for Heavy Metals?
Yes. A serving of MycelPro-1 is both cGMP Compliant and Prop-65 Compliant for Arsenic, Cadmium, Lead, and Mercury, making it one of the cleanest protein powders available.
Are Chitin and Chitosan fibers beneficial?
Chitin and Chitosan are prebiotic fibers produced by mycelium that is found in fungi but not plants, with quite a few health benefits in humans.
> Chitosan supports a healthy gut microbiome, gut barrier integrity and immune function.
> Chitosan binds to dietary fat, cholesterol and triglycerides in the gut.
* Because Chitosan binds to fats, take fat soluble supplements (ex: Vitamin E, Omegas) at least four hours before or after consuming MycelPro-1.
> Chitosan may help remove PFAS (forever chemicals) and microplastics from the body.
> Chitosan supports healthy weight management and cardiovascular health.
> Chitosan also may increase the absorption and bioavailability of Vitamin B-12.
Is Rhizomucor pusillus safe to consume?
Yes. The specific strain of Rhizomucor pusillus (CBS 143028) does not produce ycotoxins. Safety Study here: https://pubmed.ncbi.nlm.nih.gov/37532172/
Is MycelPro-1 a complete protein?
Yes, the mycelium protein in MycelPro-1 is a complete protein with all 9 EAAs. It is a good source of muscle building Leucine and Lysine and BCAAs.
Is the protein very digestible?
MycelPro-1 mycelium protein has a PDCAAS of 1.0.
What is spermidine? Is it safe? Is it synthetic, isolated or added?
Spermidine is a polyamine, that is essential for Autophagy, a cellular process that removes damaged/dead cells and is considered one of the most important ant-aging nutrients known. It is reported to be the only nutrient that positively supports “all 12 Hallmarks of Aging”.
See the Research Page to links to read additional studies on Spermidine, Chitin/Chitosan, Mycelium and more.
How is it different than plant protein powders?
> Better for muscle: Two important muscle building amino acids are Leucine and Lysine, with Lysine being a rate-limiting AA in plant foods. Gram for gram, MCP-1’s whole mycelium provides more Leucine than whole milk, whole egg and skinless chicken breast.
> MCP-1 contains Prebiotic Fibers Chitin & Chitosan, not found in plant foods.
> MCP-1 is the richest whole food source of Spermidine, 5-7 times more than most plant foods.
> MCP-1 is a whole food, where most plant protein powders are processed, concentrated or isolated and stripped of some nutrients, and fiber.
How is it different than whey protein powders?
> MCP-1 is rich in Anti-Aging Spermidine not found in whey protein.
> MCP-1 is a whole food, where whey protein powders are highly processed, concentrated or isolated.
> MCP-1 contains 10g Prebiotic Fiber not found in whey protein.
> MCP-1 not contain, dairy, casein, lactose, cholesterol and NO US Common Allergens.
Should anyone avoid using Mycelpro-1?
> Due to the high Spermidine content, anyone who has histamine intolerance (HIT), should avoid using this product.
> Avoid using if you are sensitive to Fungi.
What if you have Herpes? What is the Arginine to Lysine ratio?
MycelPro-1 has an Arginine to Lysine Ratio 1:1.3, with lower Arginine and
higher Lysine, which can be better for those with Herpes.
Plant-based proteins often have a higher arginine-to-lysine ratio, so individuals prone to Herpes outbreaks may find MycelPro-1to be a preferable option.
Learn More from the Studies Below:
MYCELIUM
2023 Mycorrhizal mycelium as a global carbon pool https://doi.org/10.3390/cells8121549
2023 Mycelium: A Nutrient-Dense Food To Help Address World Hunger, Promote Health, and Support a Regenerative Food System https://doi.org/10.1021/acs.jafc.3c03307
2025 The role of algae, fungi, and insect-derived proteins and bioactive peptides in preventive and clinical nutrition https://doi.org/10.3389/fnut.2024.1461621
PROTEIN
LYSINE STIMULATES MUSCLE GROWTH*
2019 mTORC1 Mediates Lysine-Induced Satellite Cell Activation to Promote Skeletal Muscle Growth
https://doi.org/10.3390/cells8121549
2025 Evaluation of protein intake and protein quality in New Zealand vegans https://doi.org/10.1371/journal.pone.0314889
2021 Ingestion of an ample amount of meat substitute based on a lysine-enriched, plant-based protein blend stimulates postprandial muscle protein synthesis to a similar extent as an isonitrogenous amount of chicken in healthy, young men
https://doi.org/10.1017/s0007114521004906
2020 A mycoprotein-based high-protein vegan diet supports equivalent daily myofibrillar protein synthesis rates compared with an isonitrogenous omnivorous diet in older adults: a randomised controlled trial https://doi.org/10.1017/s0007114520004481
2024 "Plant-based meat alternatives and cardiometabolic health: a systematic review and meta-analysis" https://doi.org/10.1016/j.ajcnut.2024.12.002
2020 Effects of mycoprotein on glycaemic control and energy intake in humans: a systematic review
https://doi.org/10.1017/s0007114520000756
2016 Mycoprotein reduces energy intake and postprandial insulin release without altering glucagon-like peptide-1 and peptide tyrosine-tyrosine concentrations in healthy overweight and obese adults: a randomised-controlled trial https://doi.org/10.1017/s0007114516001872
SPERMIDINE
LONGEVITY, AUTOPHAGY, HEALTHY AGING
2020 Nutritional Aspects of Spermidine https://doi.org/10.1146/annurev-nutr-120419-015419
2025 Effects of Spermidine-Rich Rice Germ Extract Supplement on Biomarkers of Healthy Aging and Autophagy-Proof-of-Concept Pilot Study https://alternative-therapies.com/oa/index.html?fid=11706
2018 Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
https://doi.org/10.1080/15548627.2018.1530929
2018 Higher spermidine intake is linked to lower mortality: a prospective population-based study
https://doi.org/10.1093/ajcn/nqy102
2014 Basis of the ‘anti-aging’effect of spermidine and other natural polyamines—a mini-review.
https://doi.org/10.1159/000356748
2009 Spermidine surprise for a long life. https://doi.org/10.1038/ncb1109-1277
2018 Spermidine delays aging in humans. https://doi.org/10.18632/aging.101517
2009 Induction of autophagy by spermidine promotes longevity https://doi.org/10.1038/ncb1975
2018 Higher spermidine intake is linked to lower mortality: a prospective population-based study.
https://doi.org/10.1093/ajcn/nqy102
FASTING
2024 Spermidine controls autophagy during fasting
https://doi.org/10.1038/s43587-024-00710-3
2024 Spermidine is essential for fasting-mediated autophagy and longevity https://doi.org/10.1038/s41556-024-01468-x
2024 Spermidine activates adipose tissue thermogenesis through autophagy and fibroblast growth factor 21 https://doi.org/10.1016/j.jnutbio.2024.109569
BRAIN HEALTH, COGNITION AND MEMORY
2025 Spermidine alleviates depression via control of the stress response https://www.biorxiv.org/content/10.1101/2024.12.04.626625v1
2025 Effects of Spermidine-Rich Rice Germ Extract Supplement on Biomarkers of Healthy Aging and Autophagy-Proof-of-Concept Pilot Study https://alternative-therapies.com/oa/index.html?fid=11706
2020 The positive effect of spermidine in older adults suffering from dementia, First results of a 3-month trial https://doi.org/10.1007/s00508-020-01758-y
2022 The Role of Polyamines in the Mechanisms of Cognitive Impairment https://doi.org/10.1134/S1819712422030059
2024 Spermidine as an epigenetic regulator of autophagy in neurodegenerative disorders https://doi.org/10.1016/j.ejphar.2024.176823
2020 Nutritional Aspects of Spermidine https://doi.org/10.1146/annurev-nutr-120419-015419
2022 Mechanisms of spermidine-induced autophagy and geroprotection
https://doi.org/10.1038/s43587-022-00322-9
2021 New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases
https://doi.org/10.14336%2FAD.2021.0603
2022 Overview of Polyamines as Nutrients for Human Healthy Long Life and Effect of Increased Polyamine Intake on DNA Methylation https://doi.org/10.3390/cells11010164
2020 Spermidine intake is associated with cortical thickness and hippocampal volume in older adults
https://doi.org/10.1016/j.neuroimage.2020.117132
CARDIOVASCULAR HEALTH
2024 Dietary polyamine intake lowers the risk of all-cause and cardiovascular disease-related mortality: Follow-up of the Korean National health and nutrition Examination survey 2007–2015 https://doi.org/10.1016/j.jff.2024.106268
2025 Effects of Spermidine-Rich Rice Germ Extract Supplement on Biomarkers of Healthy Aging and Autophagy-Proof-of-Concept Pilot Study https://alternative-therapies.com/oa/index.html?fid=11706
2016 Cardioprotection and lifespan extension by the natural polyamine spermidine ttps://doi.org/10.1038/nm.4222
2024 Protective effects of spermidine levels against cardiovascular risk factors: An exploration of causality based on a bi-directional Mendelian randomization analysis https://doi.org/10.1016/j.nut.2024.112549
LIVER AND KIDNEY HEALTH
2023 Spermidine suppresses the activation of hepatic stellate cells to cure liver fibrosis through autophagy activator MAP1S https://doi.org/10.1111/liv.15558
EYE HEALTH
2022 Research Progress and Potential Applications of Spermidine in Ocular Diseases https://doi.org/10.3390/pharmaceutics14071500
MICROBIOME AND DIGESTIVE TRACT HEALTH
2020 Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice
https://doi.org/10.1080/19490976.2020.1832857
2024 Spermidine – an old molecule with a new age-defying immune function https://doi.org/10.1016/j.tcb.2023.08.002
2023 Spermidine Ameliorates Colitis via Induction of Anti-Inflammatory Macrophages and Prevention of Intestinal Dysbiosis https://doi.org/10.1093/ecco-jcc/jjad058
IMMUNE FUNCTION
2024 Spermidine – an old molecule with a new age-defying immune function https://doi.org/10.1016/j.tcb.2023.08.002
HAIR GROWTH, HAIR LOSS, GREY HAIR
2011 Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions https://doi.org/10.1371%2Fjournal.pone.0022564
2017 A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study https://doi.org/10.5826%2Fdpc.0704a05
2021 Spermidine promotes melanin production through an MITF signaling pathway https://doi.org/10.1002/cbf.3619
SKIN/COLLAGEN
2021 Spermidine-induced recovery of human dermal structure and barrier function by skin microbiome https://doi.org/10.1038/s42003-020-01619-4
2011 Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions https://doi.org/10.1371%2Fjournal.pone.0022564
FAT LOSS & FAT ACCUMULATION
2021 Spermidine ameliorates high-fat diet-induced hepatic steatosis and adipose tissue inflammation in preexisting obese mice https://doi.org/10.1016/j.lfs.2020.118739
2021 New Insights into the Roles and Mechanisms of Spermidine in Aging and Age-Related Diseases https://doi.org/10.14336%2FAD.2021.0603
2024 Spermidine activates adipose tissue thermogenesis through autophagy and fibroblast growth factor 21 https://doi.org/10.1016/j.jnutbio.2024.109569
2025 Lactobacillus reuteri ZJ617 attenuates metabolic syndrome via microbiota-derived spermidine https://pubmed.ncbi.nlm.nih.gov/39837844/
2020 Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice https://doi.org/10.1080/19490976.2020.1832857
2021 Oral Spermidine Targets Brown Fat and Skeletal Muscle to Mitigate Diet-Induced Obesity and Metabolic Disorders https://doi.org/10.1002/mnfr.202100315
2020 Spermidine improves gut barrier integrity and gut microbiota function in diet-induced obese mice https://doi.org/10.1080/19490976.2020.1832857
2024 Spermidine – an old molecule with a new age-defying immune function https://doi.org/10.1016/j.tcb.2023.08.002
MUSCLE FUNCTION, STRENGTH, SARCOPENIA
2025 Spermidine-eIF5A axis is essential for muscle stem cell activation via translational control https://doi.org/10.1038/s41421-024-00712-w
2015 Reactivation of autophagy by spermidine ameliorates the myopathic defects of collagen VI-null mice https://pubmed.ncbi.nlm.nih.gov/26565691/
2023 Sustained oral spermidine supplementation rescues functional and structural defects in COL6-deficient myopathic mice https://doi.org/10.1080/15548627.2023.2241125
2016 Polyamines improve anti-blood lactate accumulation in an acidosis rat model http://dx.doi.org/10.4103/2322-1232.222590
2014 Lactic acidosis treatment by nanomole level of spermidine in an animal model https://doi.org/10.1016/j.yrtph.2014.08.015
2017 Spermidine coupled with exercise rescues skeletal muscle atrophy from D-gal-induced aging rats through enhanced autophagy and reduced apoptosis via AMPK-FOXO3a signal pathway https://doi.org/10.18632/oncotarget.15728
CANCER
2023 Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms https://doi.org/10.3389/fchem.2023.1164477
2022 Overview of Polyamines as Nutrients for Human Healthy Long Life and Effect of Increased Polyamine Intake on DNA Methylation https://doi.org/10.3390/cells11010164
2015 Dietary polyamine intake and colorectal cancer risk in postmenopausal women https://doi.org/10.3945/ajcn.114.103895
PARKINSON'S, DEMENTIA, ALZHEIMER'S
ALZHEIMER'S
2022 Spermidine reduces neuroinflammation and soluble amyloid beta in an Alzheimer’s disease mouse model https://doi.org/10.1186/s12974-022-02534-7
2021 Spermidine, a caloric restriction mimetic, provides neuroprotection against normal and D-galactose-induced oxidative stress and apoptosis through activation of autophagy in male rats during aging https://doi.org/10.1007/s10522-020-09900-z
ANTI-INFLAMMATORY
2021 Human RCT Polyamine-Rich Diet Elevates Blood Spermine Levels and Inhibits Pro-Inflammatory Status: An Interventional Study https://doi.org/10.3390/medsci9020022
BIOAVAILABILITY
2018 Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? https://doi.org/10.1080/15548627.2018.1530929
RAPAMYCIN
2018 Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans? https://doi.org/10.1080/15548627.2018.1530929
2024 A surge in endogenous spermidine is essential for rapamycin-induced autophagy and longevity https://doi.org/10.1080/15548627.2024.2396793
SAFETY
2023 In silico and in vitro safety assessment of a fungal biomass from Rhizomucor pusillus for use as a novel food ingredient https://doi.org/10.1016/j.fct.2023.113972
2020 Identification of longevity compounds with minimized probabilities of side effects https://doi.org/10.1007/s10522-020-09887-7
2018 Safety and tolerability of spermidine supplementation in mice and older adults with subjective cognitive decline. Aging. https://doi.org/10.18632/aging.101354
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*FDA Disclaimer: These statements have not been evaluated by the Food And Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.
